CCICHT Newsletter April 2003
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Allen, K. V., I. S. McGregor, et al. (2003). "Regional differ Delta(9)-THC induced Fos expression in rat brain." Neuropharm Recent behavioral and pharmacological research sh cannabinoid and opioid neurochemical systems. Here we exam this interaction using c-fos immunohistochemistry. We compare of male albino Wistar rats treated with vehicle, Delta(9)-tetrah i.p.), naloxone (10 mg/kg, i.p.) or THC and naloxone in com depressed in both THC treatment groups and moderately inhib Results showed that naloxone inhibited THC-induced Fos imm regions including the ventral tegmental area, ventromedial central caudate-putamen and ventrolateral periaqueductal gre had an additive effect on Fos immunoreactivity in the central nucleus of the stria terminalis (lateral division), the insular corte of the thalamus. These findings complement earlier pharma modulation of cannabinoid-induced analgesia, appetite and effects of naloxone on THC-induced ventral tegmentum, hypo Fos expression point to these structures as key sites involved in
منابع مشابه
Malcolm Price Laboratory School 4 - 1996 [ Price Laboratory School ] Newsletter , v 6 n 7 , April 1996
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تاریخ انتشار 2003